Progene: 2023 Review And Full Analysis (By An Expert)

Progene is an all-natural herbal supplement to help restore testosterone production in aging males. Here’s our complete analysis so you can decide for yourself if this is the right test booster pill for you.

Progene reviews, ratings, and buyer's guide

Progene has become a popular name lately when it comes to natural testosterone-boosting supplements.

Claiming to be a doctor-recommended formula that supports declining testosterone levels, it does look promising for gaining lean muscle mass and endurance.

On top of that, it looks like it may be able to provide increases in energy and motivation as well.

But are these claims legit and does Progene testosterone booster live up to all of the hype?

Let’s take a closer look and find out.

What Is Progene?

Progene is one of the many popular over-the-counter testosterone-boosting supplements that boasts a long list of rare herbal ingredients.

It’s aimed at successfully boosting lagging testosterone levels for increased performance and motivation.

The goal is to help your body gain the size, strength, vitality, and performance that you have lost over time and roll it back to its younger years.

The average Testosterone levels in healthy men are expected to drop by 1-2 percent every year.

This means that production will have dropped to almost 20-30 percent of its initial levels by the age of forty.

Decreased testosterone levels lead to a decrease in muscle strength and size gains, sexual drive and performance, and overall energy levels.

This is where a natural remedy like Progene can help stop this unwanted decline and restore levels to normal.

Who Should Use It?

Progene is marketed to men over 18 who have noticed age-related declines in muscle mass, energy, strength, and libido.

It may provide moderate benefits for relatively healthy men in their 40s, 50s, and 60s who eat well and exercise but still feel the effects of diminishing testosterone.

However, Progene is not recommended for:

  • Men under age 40 (too young for age-related testosterone decline)
  • Teenagers or young men whose natural testosterone production could be disrupted
  • Men with pre-existing health conditions like heart disease or diabetes
  • Men currently taking medications that may interact with ingredients
  • Men who have been clinically diagnosed with low testosterone by a doctor

Men who fall into these categories are better off avoiding testosterone boosters like Progene altogether.

Instead, they should have testosterone levels tested by a medical professional to determine if hormone therapy such as TRT or other treatment is needed.

Overall Assessment

Based on the mix of positive reviews and critical customer feedback, Progene seems to be a moderately effective testosterone booster that delivers noticeable benefits for a lot of users. However, experiences vary widely.

On the Positive Side

On the positive side, the majority of customers report meaningful improvements to energy, endurance, muscle-building capacity, and especially sexual performance after using Progene.

Many note fast-acting benefits in as little as 2-3 weeks. Users also appreciate the vitamin and mineral support for more complete results.

Potential Side Effects

However, quality control and side effects seem to be an issue for a vocal minority. Some customers report no effects at all or even worsening hormonal balance.

More concerning are accounts of potentially dangerous symptoms like liver dysfunction, cardiovascular problems, and nausea/dizziness indicating blood pressure issues.

Who Might Benefit Most

While anyone considering Progene should proceed with realistic expectations and appropriate medical guidance, for many men it does appear to provide moderate testosterone-boosting effects.

Those over 40 seem most likely to benefit. Just be aware that individual reactions differ greatly, so monitoring your biomarkers is advised.

Progene Customer Reviews

So what are customers saying?

There are several Progene user reviews on Amazon that you can take a look at and see what people who used the product are saying.

Seems to be a mix of good and bad, everything from “it works” to “Progene is a total scam”.

There are some customer complaints about Progene that are a bit of concern and should be taken seriously.

Positive Reviews

The majority of customers seem reasonably satisfied with their experience using Progene. Here are some of the most common favorable reviews:

  • Increased Energy And Stamina: Many users report feeling more energetic, stronger, and having greater endurance for workouts after taking Progene. They attribute this to boosted testosterone levels.
  • Enhanced Sex Drive And Performance: A common theme is that Progene provides a noticeable increase in libido and sexual function. Multiple older users say it improved bedroom performance to levels they hadn’t experienced in years.
  • Better Mood And Reduced Irritability: Some users mention Progene helping stabilize mood swings and reduce feelings of irritability. They say it leads to a general sense of well-being.
  • Lean Muscle Growth: Several reviewers mention putting on lean muscle more easily when using Progene in combination with exercise. The muscle-boosting effects seem more pronounced in men over 40.
  • Fast Acting: While Progene states effects can take 60-90 days to fully develop, many customers report substantial benefits after only 2-3 weeks. This exceeds expectations at the onset of action.
  • Vitamin Support: Users note and appreciate that, unlike many singe-ingredient testosterone boosters, Progene provides comprehensive vitamin support for overall health. This leads to more complete results.
  • Positive Safety Profile: Customers feel reassured by the clean safety profile. Despite being a powerful supplement, Progene does not seem to carry significant side effect risks seen with synthetic hormones.

Customer Complaints

Like with any supplement, when you read the reviews on Amazon you’re going to come across customers who just aren’t happy. Here are a few of the more common complaints from users that may cause some concern:

  • Increased Liver Enzyme Values: The trend seems to be a problem with liver enzyme values, but it is not known whether the users had problems beforehand.
  • Decrease in Testosterone: There was a complaint from a user who was involved in a Progene testosterone study and stated that his testosterone levels decreased after taking it.
  • Sick And Lightheaded: Multiple users reported feeling dizzy, nauseous, and lightheaded after taking Progene. This indicates potential issues with blood pressure regulation.
  • Zero Results: Several reviewers said they noticed no effects at all after taking Progene for the recommended period. The product did not live up to its claims for them.
  • Product Is Not Returnable: A major complaint is that Progene does not allow returns even when customers are dissatisfied. The company’s refund policy is very restrictive.
  • Pills Are Difficult To Swallow: Some users say the large capsule size and rough texture make Progene pills uncomfortable or even hazardous to swallow. This can deter people from completing the dosage regimen.
  • Cardiovascular Issues: Multiple concerning accounts of rapid heart rate, chest pain, and heart attack-like symptoms while taking Progene. Indicates potential cardiovascular side effects.

With that said it would be best to check with your physician before starting Progene and then get your liver enzymes and testosterone levels tested periodically.

How Does It Work?

Progene has a unique dual-action formula that includes a unique component that works in conjunction with a blend of herbal ingredients.

The first part is what’s termed a pro-hormone component, which works as the base for the natural production of testosterone.

Then there are the herbal components that work to promote proper utilization of the pro-hormonal components.

Main Herbal Components

The main herbal component in Progene consists of Wild Oat extract, Withania Somnifera root, and Guarana seed extract.

The job of these main herbal components is to aid in overall energy production and sustenance.

  • L- Arginine and DHEA are two components that play a major role as clinically proven testosterone precursors.
  • Eleuthero Root and Lycopene work together to enhance the body’s immune response and help increase vigor and vitality.
  • Tribulus Terrestris Root and Sarsaparilla Root help to increase sexual energy and performance while helping to increase lean muscle mass and strength.

Pro-Hormonal Activators

Progene has two main clinically proven testosterone precursors, DHEA and Muira Puama extract.

These act as the Pro-Hormone activators for the herbal ingredients to help the body to naturally manufacture more testosterone.

On their own, they aid in enhancing motivation and a positive outlook that leads to better physical and mental performance.

Progene is not an overnight cure-all though.

The dual action formula is designed to work over the long term and that’s why it’s advised to take Progene daily for several months to see the best results.

Progene Ingredients

Progene contains several popular testosterone-boosting ingredients that you can find in other over-the-counter formulas.

Let’s take a closer look at each of the ingredients and see how they can help you increase your testosterone levels naturally.

Progene Ingredients Nutrition Label

L-Arginine HCL

L-arginine is a doctor-recommended supplement that has been clinically proven to help your body to naturally increase NO2 which results in greater muscle mass and huge skin-stretching pumps.

This is why it’s a fundamental ingredient in most pre-workout supplements.

As stated, it metabolizes easily into Nitric Oxide (NO2), which is key for improved blood flow and getting those coveted pumps in the gym.

Better blood flow has an immense number of other health benefits as well, including improved cardiovascular health, improved sexual function, helping your body remove harmful toxins, and more.

Although L-Arginine can be obtained through a healthy diet, a supplement will help produce even greater amounts of NO2 and result in significant benefits.

Tongkat Ali 50:1 Extract (Eurycoma Longifolia Root)

Eurycoma Longifolia, or “Long Jack” as it is well known, is a common ingredient in testosterone supplements that comes from a rare herb in Asia.

Long Jack is considered one of the more potent natural testosterone boosters because it is said to help your system more effectively produce testosterone.

It’s also known to improve stamina, endurance, and energy and skyrocket libido.

Guarana Seed Extract (Paullinia Cupana)

Native to Brazil and Venezuela, the Guarana plant technically known as ‘Paullinia Cupana’, produces a seed with many performance-enhancing benefits.

It’s an intense energy booster and often found in diet pills since it contains generous amounts of natural caffeine, even more than your daily cup of coffee.

This extra added energy helps to give you both the workout intensity and endurance that you need to grind out those brutal training sessions.

It has also been reported to help with weight loss and is even used as a stress reliever.

DHEA (Dehydroepiandrosterone)

DHEA is one of the most, if not the most popular pro-hormone testosterone supplement on the market today that is used in building muscle and anti-aging.

Regarded as a great overall health supplement, it’s involved with many different biological processes, from improving bone density to boosting the immune system.

Studies have also shown the benefits of DHEA in helping to control and even decrease the growth of fat cells.

Saw Palmetto (Berry Extract)

Saw Palmetto Extract is a popular name among testosterone boosters because it always seems to be one of the main ingredients in just about every product out there.

Saw Palmetto is unique because it can limit the production of several test-binding enzymes in the body.

By doing so, healthy free testosterone levels can be maintained.

Damiana Leaf

Damiana is a shrub that grows in North America, Central America, Mexico, South America, and the Caribbean.

Men have traditionally found success using the leaves of the Damiana plant because of its ability to increase sexual desire and performance while decreasing impotence. [1]

Damiana is also known for its antidepressant qualities and helping to decrease anxiety while improving sexual health.

Sarsaparilla Root

Sarsaparilla Root has been used as a tonic in traditional herbal medicine to help increase the production of male hormones.

It has long been used by locals in South American regions to improve sexual vigor, stamina, and overall health.

Sarsaparilla Root comes with additional benefits for bodybuilders and has been used for years by lifters for its ability to help increase lean body mass and improve endurance.

Ginger Root

Ginger has a reputation as an excellent herbal tonic for helping to improve digestion and control nausea.

It contains powerful antioxidant properties, making it useful for even the common cold as well as digestive issues.

But what most people don’t know is that this wild Amazonian shrub has been traditionally used for centuries as a sexual enhancer for native Brazilians.

More recent clinical studies have scientifically proved it to be true.

Muira Puama (Aerial Parts Extract)

Muira Puama Concentrate helps to naturally increase testosterone levels, which makes it not only an ideal sexual enhancer but an ideal bodybuilding supplement as well.

This root has been used as a tonic to help enhance general health and well-being, improve memory capabilities, increase stamina, and boost vigor.

Siberian Ginseng (Eleutherococcus Senticosus)

Eleuthero, otherwise known as Siberian Ginseng, is one of the most powerful herbal “adaptogens”.

Adaptogens are herbs that are used to support the body and help it to “adapt” during times of high stress or great physical exertion.

Eleuthero has been used medicinally for thousands of years in Eastern traditions to help increase both physical and mental stamina while improving an overall sense of well-being.

Ginseng Root Blend (Korean, Chinese Red Panax, And Tienchi)

Another very popular herbal adaptogen is Ginseng, which comes in many different forms.

Found in several areas of Asia, Ginseng has been around for nearly five thousand years and is used medicinally in a variety of different cultures.

The energy and overall health benefits are said to be the result of chemical compounds found in Ginseng called ginsenosides.

Recent research has also shown that Ginseng can provide benefits in the treatment of erectile dysfunction. [2]

Oat Straw Extract (Avena Sativa)

Known also as “Avena Sativa”, oat straw contains large amounts of avenocosides, the active component that may help to increase testosterone.

Avena Sativa works by freeing up bound testosterone and thus can increase levels of free testosterone.

Free testosterone is the only form that matters for building muscle mass.

Stinging Nettle Leaf Extract (Urtica Dioica)

Stinging Nettle is found throughout many of the mountainous regions in the U.S.

The name is appropriate since the plant itself is dangerous to the touch and can cause a painful rash.

Concentrating the plant’s roots, on the other hand, may provide many health-related benefits.

One of the main benefits of Stinging Nettle is the role it plays in inhibiting aromatase, an enzyme that converts testosterone to estrogen.

Another benefit is its role in freeing up testosterone by binding with SHBG, a protein that is known for binding to testosterone and making it inactive.

Lycopene

Lycopene is a popular supplement for men and is the pigment that gives many fruits and vegetables such as tomatoes their red color.

Lycopene is beneficial in helping health issues in men such as cardiovascular disease, joint inflammation, and prostate health.

Mucuna Puriens (Seed)

Mucuna Puriens, also known as Velvet Bean in some areas, is an ancient medicinal herb that is found in areas of India and China.

Rich in L-Dopa, it has been used for many years in the treatment of a vast number of ailments, from male infertility to diabetes.

Studies have shown that Mucuna Pruriens can significantly increase levels of Testosterone, Luteinizing hormone, Dopamine, Adrenaline, and noradrenaline levels. [3]

The same study showed a reduction in Follicle-Stimulating Hormone and Prolactin levels while sperm count and motility were significantly recovered.

Withania Somnifera (Root)

Better known as Ashwagandha, this small shrub located in areas of India and Africa has been proven in many clinical trials to be beneficial for male health.

In a study with men ages 50-59, those who took a Withania Somnifera root supplement for 12 months saw lowered cholesterol, healthier red blood cells, improved sexual performance, and stronger immune systems.

Licorice (Root)

Sometimes referred to as “sweet root”, Licorice is an adaptogen herb that has long been used to improve focus and concentration.

Licorice has also been used for stabilizing blood sugar, and combating adrenal fatigue and has been proven to act as a powerful antioxidant. [4]

Tinospora-Cordifolia (Leaf)

Native to India, Tinospora Cordifolia has long been used in Ayurvedic medicine because of its antioxidant functions and ability to boost the immune system.

There have also been reports that it helps to improve cognition, memory, and concentration.

This herb also can lessen joint pain and even improve kidney function.

Nutmeg (Seed)

Nutmeg comes from a tree called Myristica Fragrans.

The seed of the nut has been used for centuries to improve digestion.

It helps the body to absorb more nutrients and also acts as an antioxidant.

Tribulus Terrestris (Root)

Tribulus Terrestris has long been used in the bodybuilding world and is one of the most popular testosterone-boosting supplements because of its fail-proof results.

Both strength and physique athletes alike call it their “secret weapon” for winning competitions.

There is a reason that it is one of the top testosterone-boosting ingredients on the market.

Tribulus has shown time and time again its benefits for improved muscle growth, stamina, libido, and fertility in men.

Safety And Side Effects

Most of the ingredients in Progene are generally recognized as safe, but some users have reported side effects like:

  • Stomach discomfort, nausea, or diarrhea
  • Increased aggression and irritability
  • Acne breakouts
  • Excess body hair growth
  • Breathing difficulties
  • Sleep disturbances

Progene may also negatively interact with certain medications like blood thinners, antidepressants, and blood pressure drugs. As with any supplement, it’s advisable to consult a doctor before use.

Frequently Asked Questions (FAQ) About Progene

Is Progene a supplement only for athletes?

In general, it’s not. While including a proper diet and regular exercise program is always beneficial, it is not completely necessary to see results.

How much do I take per serving? And when should I take them?

You only have to take one serving (2 capsules) of Progene once per day. Progene should always be taken after a meal.

How does the shipping process work?

If you order before 4 p.m. (Eastern Standard Time), your package will begin shipping by the next business day. Most shipments arrive within 2-5 days (in the United States). Ordering and shipping runs Monday through Friday.

Review Summary: Should You Buy Progene?

So is Progene the best test-booster supplement out there on the market? Probably not.

Some concerns with this supplement would have me believe it’s not the best one out there.

In fact, there are far better test boosters that have not had any reported side effects from users.

My Recommendation:

With that said, I would skip Progene and play it safe with a trusted product like TestoPrime that has a solid track record.

TestoPrime has been proven both safe and effective for boosting testosterone levels in men and comes with a risk-free money-back guarantee.

Don’t take my word for it though; take a look at what users are saying about our #1 rated testosterone booster on the market today and then decide for yourself.

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About Gabe Ramsey, BS, CSCS

Gabe is a Certified Strength and Conditioning Specialist and Senior Editor here at GeoLeaders.com. He holds a Bachelor’s in Exercise and Sport Science along with over 15 years experience providing world-class training, coaching, and consulting for bodybuilders, strength athletes, and physique competitors. Gabe provides science-based fitness education with proven expertise in strength and hypertrophy programming, high-performance nutrition, nutritional supplementation, and body recomposition. Follow Gabe on Twitter and connect with him on LinkedIn.